The invention discloses a high-yield, green and environment-friendly cultivation method for sweet potatoes with reduced chromium and enriched selenium, zinc and iron. The method comprises the following steps: step 1, selecting seeds; step 2, preparing a selenium, zinc and iron enriched nutrition agent; step 3, breeding seedlings; 4, carrying out management in a seedling stage; 5, carrying out soilpreparation; step 6, planting sweet potato seedlings; step 7, carrying out field management; and step 8, carrying out harvesting. With the high-yield, green and environment-friendly cultivation method for the sweet potatoes with reduced chromium and enriched selenium, zinc and iron, the sweet potatoes have high yield and good economic benefits; a base fertilizer of a selenium, zinc and iron enriched compound fertilizer is added during the seedling breeding period of the sweet potatoes, and the fertilizer is uniformly dispersed in the soil, so that potato seedlings are ensured to fully absorbthe enriched selenium, zinc and iron fertilizer; simultaneously, heavy metals in the soil are separated out through the complexation of a surfactant, so that the content of the heavy metal chromium inthe soil is effectively reduced, and the cultivation method is green and harmless, and has a relatively high value and a good application prospect.