The invention discloses an optimal setting method for parameter lubricating parameters of a secondary cold rolling unit under a small deformation condition. By considering the equipment and process characteristics of a cold continuous rolling mill unit fully, the condition of guaranteeing that no slip and Jumping phenomena exist in strip steel is used as a control object. The optimal emulsification solution concentration, the optimum flow and the optimum initial temperature are sought under the circumstance that the emulsion solution quality, the rolling process parameters (steel type, specification, reduction rate, rolling speed and front and back tensions) and the rolling process parameters (working roller diameter and original surface roughness) are determined. Therefore, the productionstability of the unit is improved, and benefits are brought to enterprises.