The invention discloses a method for producing a 600g zinc layer spangle-free hot galvanized plate based on a thin slab continuous casting and rolling hot-radical raw material and an acid plating continuous production line, belongs to the technical field of steel, and relates to a method for producing a 600g zinc layer spangle-free hot galvanized plate based on a full headless thin slab continuouscasting and rolling hot-radical raw material and an acid plating continuous production line. The method comprises the following technological steps that a raw material reel is produced through the full headless thin slab continuous casting and rolling procedure, and then is subjected to pickling, leveling, heating, galvanizing, finishing and passivating and wound into a hot galvanized reel. Through the method, the 600g zinc layer spangle-free hot galvanized plate with the specification being 2.0-3.0 mm*1500 m can be stably produced, and the product is good in surface quality, high in size precision and stable in performance and can simultaneously replace traditional cold and hot radical products.