The invention discloses a release paper stripping device. The release paper stripping device comprises a rack and two sets of stripping device bodies oppositely arranged on the two sides of the rack.Each stripping device body comprises a first separation wheel, a second separation wheel, an upper clamping device and a lower clamping device, wherein the first separation wheel and the second separation wheel are coaxially arranged in the vertical direction; the upper clamping device and the lower clamping device are correspondingly arranged at the eccentric positions of the first separation wheel and the second separation wheel; and the first separation wheel and the second separation wheel can relatively rotate in opposite directions. The two first separation wheels on the two sides of therack are parallel with each other. Firstly, synthetic leather and two angles of the end portions of release paper are subjected to pre-separation, then the upper clamping devices and the lower clamping devices on the two sides are used for clamping and fixing the pre-separated synthetic leather and the release paper, then the first separation wheels and the second separation wheels rotate in opposite directions, the upper clamping devices and the lower clamping devices are correspondingly made to be away from each other up and down in the peripheral direction, and therefore the synthetic leather is separated from the release paper, operation is easy, and the separation effect is good.