A multi-channel purifier for removing air-borne microbial particles. At least two filter modules (1) are provided in the purifier; a plurality of purification units (2) are provided in each filter module (1); and each purification unit (2) accelerates an airflow using an airflow jet device (4), so that air-borne microbial particles land on a particle collection plate (6) due to inertia. A plurality of jet acceleration nozzles are provided on the airflow jet device (4), and a plurality of collection grooves are formed in the collection plate (6); the nozzles correspond to the grooves, and an ultraviolet sterilization lamp (5) is provided in each purification unit (2) and is used for carrying out irradiation inactivation on the collected microbial particles. The filter modules are connected therebetween in a cascading manner, and a fan is provided between the filter modules. The multi-channel purifier for removing air-borne microbial particles solves the problems of the inertial impact of the particles and the reduction of collection efficiency when the required amount of clean air changes; meanwhile, the ultraviolet inactivation of captured microbial particles is achieved, so that a good control effect on a bioaerosol for indoor environments is guaranteed.