The invention discloses a friction generator with a nano-structure, comprising a top layer power generation sheet, a middle layer power generation sheet and a bottom layer power generation sheet whichare sequentially distributed from top to bottom, wherein the upper surface of the top layer power generation sheet, the lower surface of the bottom layer power generation sheet, the upper surface ofthe middle layer power generation sheet and the lower surface of the middle layer power generation sheet are all provided with metal thin film layers; the lower surface of the top layer power generation sheet and the upper surface of the bottom layer power generation sheet are both provided with organic material thin film layers; the metal thin film layer on the upper surface of the middle layer power generation sheet is electrically connected to the metal thin film layer on the lower surface of the middle layer power generation sheet; conductive rings are respectively disposed on the lower surface of the top layer power generation sheet and the upper surface of the bottom layer power generation sheet, and concave-convex structures from nano-scale to micro-scale are respectively disposed on the organic material thin film layer on the top layer power generation sheet and the organic material thin film layer on the bottom layer power generation sheet. The generator is capable of maximizing the amount of power generated in a limited space, and achieving maximum energy self-detection without additional power consumption at the same time.