The invention provides a bead stringing structure of a full automatic bead stringing machine. The bead stringing structure comprises a bead stringing bracket, a left cover closing component and a right cover closing component are mutually matched and are arranged on the bead stringing bracket, the left cover closing component comprises a left traction block, a plurality of left cushion blocks, a plurality of left guide blocks and a plurality of left pressing blocks, the right cover closing component comprises a right traction block, a plurality of right cushion blocks, a plurality of right guide blocks and a plurality of right pressing blocks; the left guide blocks and the right guide blocks are respectively located on the upper sides of the left cushion blocks and the right cushion blocks, an arc left leading wire groove and an arc right leading wire groove are respectively arranged in the end faces of the adjacent sides of the left guide block and the right guide block, the left leading wire groove and the right leading wire groove are closed to define a channel which allows a leading wire to go through, a cutting rod is arranged in the left guide block, and a relief hole is arranged in the right guide block. The ordered beads are stringed to be mutually connected together, the stringing is simple and fast, the degree of automation is relatively high, the bead stringing efficiency is greatly improved, and the product quality is improved.