Teh embodiment of the invention discloses a method and a device for determining reservoir parameters based on a three-dimensional elasto-electric rock physical quantity edition. The method comprises steps: actually-measured three-dimensional elasto and electric parameter data of a target stratum are acquired; the actually-measured three-dimensional elasto and electric parameter data are projectedto a pre-built three-dimensional elasto-electric rock physical quantity edition, and projection points are acquired, wherein building of the three-dimensional elasto-electric rock physical quantity edition comprises sub steps: three-dimensional reservoir parameter space is subjected to meshing subdivision processing, corresponding elasto and electric parameter data of a mesh node are calculated, and the three-dimensional elasto-electric rock physical quantity edition is acquired; the distance between the projection point and each mesh node is calculated, and according to the reservoir parameter of a mesh node corresponding to the minimum distance value, the reservoir parameter data of the projection point are determined; and according to the reservoir parameter data of the projection point, the reservoir parameter data of the target stratum are determined. By using each embodiment of the invention, the accuracy of reservoir parameters used for oil and gas detection can be improved.