A deadlock-free control method for an automated manufacturing system containing uncontrollable events is disclosed. The deadlock-free control method includes: acquiring a feasible step size of an automated manufacturing system containing uncontrollable events through a feasible step size online generation algorithm of a partially controllable and fully considerable automated manufacturing system;acquiring an optimal step size of the automated manufacturing system containing the uncontrollable events through the optimal step size online generation algorithm of the partially controllable and fully considerable automated manufacturing system, and performing prediction on the optimal step size of the automated manufacturing system containing the uncontrollable events in the current state so as to avoid deadlocks. The invention adopts the real-time online operation policy of synchronous prediction and control, and does not need to design a controller in advance. According to the state predicted in the current state, analysis and determination are performed, the determination result is timely fed back to the controller, and the controller makes an appropriate control decision to determine the transition needing to be transmitted in the current state, thereby avoiding deadlocks during processing.