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Invention Grant
CN108977545B 一种卵巢癌诊断或预后组合物及其应用 有权

一种卵巢癌诊断或预后组合物及其应用
Abstract:
本发明公开了一种卵巢癌诊断和预后组合物及其应用。一种卵巢癌诊断或预后组合物，由PDK1、PRKAA2和PRKAB1组成。本发明所述的卵巢癌预后组合物在制备卵巢癌诊断试剂盒或预测卵巢癌预后情况的试剂盒中的应用。一种用于预测卵巢癌预后情况的试剂盒，包含检测PDK1、PRKAA2和PRKAB1表达量的试剂。联合检测PDK1、PRKAA2以及PRKAB1三者可以有效判断卵巢癌患者预后，而单一检测其中任何一个指标均无法有效判断卵巢癌患者的预后情况。本发明为临床提供了有效的预后指标。
Abstract(English):

The invention discloses an ovarian cancer diagnosis or prognosis composition and application thereof. The ovarian cancer diagnosis or prognosis composition is composed of PDK1, PRKAA2 and PRKAB1. Theinvention provides the application of the ovarian cancer prognosis composition to preparation of an ovarian cancer diagnosis kit or a kit for predicating a prognosis condition of ovarian cancer. The kit for predicating the prognosis condition of the ovarian cancer comprises a reagent for detecting an expression amount of the PDK1, the PRKAA2 and the PRKAB1. The PDK1, the PRKAA2 and the PRKAB1 aredetected in a combined manner, and the prognosis of a patient with the ovarian cancer can be effectively judged; any index in single detection cannot be used for effectively judging the prognosis condition of the patient with the ovarian cancer. The composition disclosed by the invention provides effective prognosis indexes for clinical application.

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