The invention relates to the technical field of intelligent equipment, in particular to a man-machine interactive intelligent housekeeping robot. The man-machine interactive intelligent housekeeping robot comprises a box body, a rolling mechanism, a touch control all-in-one machine, a containing mechanism and a gravity center adjusting mechanism. When the man-machine interactive intelligent housekeeping robot goes upstairs and downstairs, a rotating motor can drive a sliding plate to rotate clockwise to enable a heavy block to move downwards, therefore, the purpose that the gravity center skews to the position same as the movement direction when the robot goes upstairs and skews to the position opposite to the movement direction when the robot goes downstairs is achieved, the inclined gravity in the process of going upstairs and downstairs is balanced, and the stability that the robot goes upstairs and downstairs is improved; the structure is flexible and changeable, the daily object containing and delivering needs of a user can be met, the robot can be folded when the robot is not used, and therefore the occupation area is small; and a supporting net can be formed through hangingropes, therefore, objects with different sizes are supported, each winding mechanism is separately installed in a first supporting pipe, and using and storing are convenient.