The invention provides a multifunctional makeup brush and a manufacturing method thereof. Main components of the makeup brush are composed of a hair protection cover and a brush body; the brush body comprises a foundation makeup brush part, an oblique eyebrow brush part, an eye shadow brush part and a uniform powder brush part, one brush body can meet the functions of the four brushes of a foundation makeup brush, an oblique eyebrow brush, a uniform powder brush and an eye shadow brush, and the multifunctional makeup brush is convenient to store and carry; a highly transparent material is usedas the material of a handle and a mouth tube and a brush type can be visually seen, and convenience is provided for choosing; an europium-containing synthetic fiber is used as the material of bristles, when the brush is used by multiple people, mite parasitism is effectively prevented, and cross-infection is prevented.