The invention discloses a preparation method and applications of a super hydrophobic oleophobic material with pH responsiveness. The preparation method comprises following steps: kaolin is added intoan ethanol solution of perfluorocapylic acid, after uniform mixing, an ethanol solution of silane is added, an obtained mixture is heated to 50 to 60 DEG C with stirring, thermal insulation is carriedout for 2 to 4h so as to obtain a suspending solution, the suspending solution is used for coating the surface of a substrate, and drying is carried out so as to obtain the super hydrophobic oleophobic material with pH responsiveness. The super hydrophobic oleophobic material possesses excellent super hydrophobicity and lipophobicity, and excellent wear resistance and corrosion resistance; in-suit or ex-situ pH induced material surface wetability change can be caused; a plurality of conversions between the hydrophobicity and lipophobicity can be realized. The super hydrophobic oleophobic material can be used for effective separation of a plurality of types of oil water mixtures, and especially treatment of oil-in-water emulsion, and the application prospect in treatment of leaked crude oil and purification of oil-containing waste water is promising.