The invention discloses temperature-sensitive printing paste, which is prepared from the following raw materials in parts by weight: 0.5 to 3 parts of a binder, 0.5 to 19 parts of a temperature changematerial, 10 to 50 parts of a crosslinking agent and 2 to 5 parts of a thickener. Meanwhile, the invention further provides a temperature-sensitive color printing process, comprising the following steps: S1, slurrying: uniformly mixing the binder, the temperature change material, the crosslinking agent and the thickener to obtain the temperature-sensitive printing color paste; S2, bleaching and dyeing; S3, setting before printing; S4, printing: feeding the temperature-sensitive printing paste obtained in the step S1 into a screen, and covering cloth by the temperature-sensitive printing pasteto obtain printed cloth C; S5, drying and baking: drying and baking the printed cloth C. The temperature-sensitive printing paste has the beneficial effects that the temperature-sensitive printing paste is high in safety and high in color change sensitivity; the printing process is simple; the color of the prepared color change cloth sensitively changes with temperature, and the color change cloth is firm in color, high in safety and suitable for being used in infant products.