The invention discloses a crossing high-angle thrust water-rich sand-rich fault tunnel excavation and drainage construction method. A tortuous pilot tunnel and a water release hole are formed in the same side of a front hole of a construction tunnel. The construction process includes the steps: first, preliminarily excavating and constructing a rear tunnel section; second, synchronously excavatingand constructing the rear tunnel section and a drainage hole body of the water release hole; third, synchronously excavating and constructing the rear tunnel section, the drainage hole body of the water release hole and a rear tortuous pilot tunnel section; fourth, constructing a front water release hole body, a front pilot tunnel section and a middle tunnel section; fifth, constructing a front tunnel section. The method is reasonable in design, simple and convenient in construction and good in use effect, water on an upper wall of a fault is drained by the high-level water release hole between the front hole of the tunnel and the tortuous pilot tunnel, drainage is assisted by the tortuous pilot tunnel excavated before the front hole of the tunnel, the front fault condition of a tunnel face of the front hole is verified in advance, the water in the fault can be maximally drained, water pressure in the front fault of the tunnel face is reduced, construction safety of each tunnel face can be ensured, and construction period is shortened.