The invention provides a holographic laser projection physical examination device. The holographic laser projection physical examination device comprises a chamber and a projector. The projector is located on the side face of the chamber, and the projection direction of the projector is located on the vacant land in front of the chamber. A chamber door and an inner chamber are arranged on the front face of the chamber. The chamber door is fixedly mounted on the inner chamber through hinges. According to the holographic laser projection physical examination device, the queuing waiting time of people in the hospital is greatly shortened, and the general check-up efficiency of the hospital can be improved; compared with a traditional examination mode, the holographic laser projection physicalexamination device accords with the fast rhythm of the society better; compared with a visual examination result, an examinee is not confused any more and can know own physical examination conditionin the first place, and based on the newest holographic laser projection technology, the examination result can be understand and accepted by people more visually and accurately.