The invention provides a novel bionic array sensor based on quantum dot fluorescence quenching. The array sensor is constructed by using cadmium telluride quantum dots as fluorescent dyestuff and using different buffer solutions in different concentration gradients as a buffer system. Compared with an array sensor requiring multiple types of organic dyestuff as reaction dots, the array sensor is formed by using only one type of quantum dots in combination with the buffer solutions in different concentrations and types, and therefore the array sensor has the advantages of being easy to make, low in cost, easy to produce in mass and the like and can be widely applied to identification of multiple types of samples rich in organic acid.