The invention relates to the field of sewage treatment devices, and particularly discloses an anti-blockage environment-friendly sewage treatment device which comprises a treatment box and further comprises a pretreatment tank. A fixed frame of the treatment box is arranged on a base. A partition plate is fixedly erected in an inner cavity of the treatment box. A waste collecting cavity is formedin the portion, above the partition plate, of the inner cavity of the treatment box. A stirring treatment cavity is formed in the portion, below the partition plate, of the inner cavity of the treatment box. A filtering cylinder is fixedly erected in the waste collecting cavity along the axis of the waste collecting cavity. The filtering cylinder penetrates through the middle of the partition plate. A filter screen is erected on the top of the filtering cylinder. A cleaning part is arranged on the upper surface of the filter screen along the axis of the filter screen. A smashing mechanism is arranged in the pretreatment tank. By means of the anti-blockage environment-friendly sewage treatment device, through the smashing mechanism arranged in the pretreatment tank and the cleaning part matched with the surface of the filter screen, the filter screen can be effectively prevented from being blocked; filtered sewage enters the mixing treatment cavity to be mixed with reagents, so the sewage treatment effect is ensured.