The invention relates to the technical field of natural gas pressure regulating, in particular to a residual pressure comprehensive utilization system of a natural gas regulator station. The residualpressure comprehensive utilization system of the natural gas regulator station comprises a natural gas pressure regulating device, a power generation device and a refrigeration house refrigerating device. The natural gas pressure regulating device comprises a prime motor, a first condenser and a temperature regulator. The power generation device comprises a generator, the prime motor is coaxiallyconnected with the generator, and the generator is connected with an outer power grid. The refrigeration house refrigerating device comprises a first compressor, a first throttle valve, a refrigeration house warehouse and a refrigeration house supplementary refrigerating device. A first evaporator and a second evaporator are arranged in the refrigeration house warehouse. According to the residualpressure comprehensive utilization system of the natural gas regulator station, the pressure difference generated in the natural gas pressure regulating process can be utilized for power generation, and in addition, the refrigeration house warehouse can be cooled through residual cold generated in the natural gas pressure regulating process.