The invention relates to the field of sensors, in particular to a temperature and humidity sensor with an intelligent interface. The system comprises a main MCU chip, a gesture recognition sensor, a power supply system, an input matrix, a USB interface, an operation information feedback module and a debugging starting module. The main MCU chip reads gesture action information captured by the gesture recognition sensor, and outputs the read information instruction to the upper system as a corresponding USB HID key value, thereby realizing a function of inputting an instruction to the system through a gesture. Instruction control of an operator can be achieved without any entity contact, and the instruction control system is novel and reasonable in design, convenient to achieve, low in cost,high in working reliability, high in practicability and high in application and popularization value.