The invention discloses an AI medical integrated machine with a bill printing function. The AI medical integrated machine comprises a machine body, wherein the machine body is provided with a displayscreen, a voucher printing assembly and a control system; the display screen comprises an expansion screen arranged on the back of an operation screen on the front of the machine body; the bottom of the operation screen is rotatably arranged on the machine body; an opening wrench is arranged on the side surface of the machine body; the opening wrench is connected with the top of the operation screen through a driving lever; the voucher printing assembly comprises a printer arranged in the machine body, and a paper exit; a communication assembly comprises an interface arranged below the operation screen. According to the AI medical integrated machine, a signal is sent manually or sent by the control system to ensure that the opening wrench moves downwards, the top of the operation screen ispulled out of the driving lever and then turned outwards, the printer is exposed, and the paper roll of the printer can be replaced, and the printer can be replaced to complete the paper change or maintenance work of the printer and realize clinic charging and medical treatment, so that the degree of automation is high, the medical treatment process is simplified, higher humanization is provided,and the medical experience is improved.