The invention aims to provide an Al-Zn-Mg-Cu aluminum alloy profile with high stress corrosion resistance and a preparation method thereof. The aluminum alloy material is prepared from, by mass, smaller than or equal to 0.1% of Si, smaller than or equal to 0.1% of Fe, 0.12%-0.14% of Cu, 0.23%-0.25% of Mn, 0.75%-0.8% of Mg, 0.15%-0.17% of Cr, 5.7%-5.8% of Zn, 0.16%-0.19% of Zr, 0.02%-0.04% of Ti, wherein the ratio of Fe to Si ranges from 1.8 to 2.5, and the ratio of Zn to Mg is controlled to range from 7.1 to 7.7. The preparation method comprises the steps of smelting, refining, essence melting, casting, homogenization annealing, extruding, solid solution quenching, stress relieving and aging treatment. According to the Al-Zn-Mg-Cu aluminum alloy profile with the high stress corrosion resistance and the preparation method thereof, the material shows good mechanical strength and stress corrosion resistance, and the material is especially suitable for aluminum alloy structural members which are prone to stress corrosion and failure, in particular to aluminum alloy structural members subjected to tensile stress at the bottom of a rail transit or a vehicle body.