The invention relates to a crop rotation planting method of poria cocos and pueraria lobata. The method specifically comprises the following steps: selecting an appropriate cultivated land, cultivating poria cocos strain basswood in the field from April to May of the first year, harvesting the poria cocos for the first time around October of the same year, harvesting the poria cocos for the secondtime from April to May of the second year, and arranging the cultivated land; carrying out pueraria lobata transplantation after two times of harvesting the poria cocose and arrangement of the cultivated land, pruning branches of the pueraria lobata in winter of the same year or spring of the second year, repeating branch pruning in winter of the second year or spring of the third year, harvesting the pueraria lobata on October of the third year, airing the cultivated land after harvesting and continuing to cultivate the poria cocos from April to May of the next year. According to the crop rotation planting method of the poria cocos and the pueraria lobata, soil, environment, cultivation and harvesting of the two economic crops are comparatively analyzed according to the planting situation of the poria cocos and the pueraria lobata in the dabie mountain area, and the crop rotation mode of the poria cocos and the pueraria lobata is provided, so that the damage of artificial cultivationto the ecological environment is reduced to the greatest extent.