The invention discloses a degradation strain of a pyrethroid insecticide and application thereof. The degradation strain is Stenotrophomonas acidaminiphila strain ZH-01 and is preserved at China Center for Type Culture Collection on November 28, 2016, and the preservation number is CCTCC NO:M 2016688. The strain can effectively degrade pyrethroid insecticides such as bifenthrin in a short period of time, has significant biodegradation effect, can be used for repairing natural environments such as water and soil contaminated by the pyrethroid insecticides such as bifenthrin, can be directly used for reducing the residual amount of the pyrethroid insecticides such as bifenthrin in water and soil by 80% or above, solves the problem of excessive pyrethroid insecticide residues in agriculturalproduction and environmental pollution problems, and is wide in application prospects.