The utility model relates to a mixing drum for preparing printing adhesives, which comprises a drum body 3 and a drum cover 2, wherein the drum body 3 comprises a jacket; an inner jacket is made of acid-resisting and alkaline-resisting stainless steel or enamel; a water inlet and a water outlet are arranged on an outer jacket; the water inlet 4 is arranged at the lower part of the drum body 4; the water outlet 5 is arranged at the upper part of the drum body; a mixing port is formed on the drum cover 2; and a high-speed dispersion machine stirring paddle 1 is used for mixing through the mixing port. Through the use of the mixing drum, heat generated during high-speed mixing process can be taken away in time, the performance of the printing adhesive is ensured, and the stability of the printing quality is improved.