Invention Grant
- Patent Title: Linear guanidine derivatives, methods of preparation and uses thereof
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Application No.: US15517764Application Date: 2015-10-09
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Publication No.: US10004702B2Publication Date: 2018-06-26
- Inventor: Maurizio Botta , Giorgio Maccari , Stefania Sanfilippo , Filomena De Luca , Jean-Denis Docquier , Davide Deodato
- Applicant: LEAD DISCOVERY SIENA S.R.L.
- Applicant Address: IT Castelnuovo Berardenga Siena
- Assignee: LEAD DISCOVERY SIENA S.R.L.
- Current Assignee: LEAD DISCOVERY SIENA S.R.L.
- Current Assignee Address: IT Castelnuovo Berardenga Siena
- Agency: Lucas & Mercanti, LLP
- Priority: ITRM2014A0580 20141010
- International Application: PCT/EP2015/073467 WO 20151009
- International Announcement: WO2016/055644 WO 20160414
- Main IPC: A61K31/155
- IPC: A61K31/155 ; C07C279/12 ; C07C279/24 ; C08K5/31 ; C07C279/04 ; A61K45/06 ; A61K31/17

Abstract:
The present invention relates to linear guanidine derivatives, methods of preparation, uses and pharmaceutical compositions thereof. The compounds of Formulas 1 or 2 exhibit high antimicrobial activity against Gram positive and Gram negative bacteria.
Public/Granted literature
- US20170304235A1 LINEAR GUANIDINE DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF Public/Granted day:2017-10-26
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