Invention Grant
- Patent Title: Constructs containing multiple expression cassettes for cancer therapy
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Application No.: US14871187Application Date: 2015-09-30
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Publication No.: US10004813B2Publication Date: 2018-06-26
- Inventor: Avraham Hochberg , Doron Amit
- Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
- Applicant Address: IL Jerusalem
- Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- Current Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- Current Assignee Address: IL Jerusalem
- Agency: Winston & Strawn LLP
- Main IPC: C12N15/85
- IPC: C12N15/85 ; A61K48/00 ; A61K38/16
Abstract:
The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More specifically, the invention provides compositions and methods utilizing a nucleic acid construct enabling expression of a cytotoxic gene product directed by more than one tumor specific promoter.
Public/Granted literature
- US20160015834A1 CONSTRUCTS CONTAINING MULTIPLE EXPRESSION CASSETTES FOR CANCER THERAPY Public/Granted day:2016-01-21
Information query
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