• Patent Title: 2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors
  • Application No.: US14899335
    Application Date: 2014-06-17
  • Publication No.: US10005769B2
    Publication Date: 2018-06-26
  • Inventor: Johann LebanMirko Zaja
  • Applicant: 4SC DISCOVERY GMBH
  • Applicant Address: DE Planegg-Martinsried
  • Assignee: 4SC AG
  • Current Assignee: 4SC AG
  • Current Assignee Address: DE Planegg-Martinsried
  • Agency: Millen, White, Zelano & Branigan, P.C.
  • Priority: EP13172577 20130618
  • International Application: PCT/EP2014/062774 WO 20140617
  • International Announcement: WO2014/202638 WO 20141224
  • Main IPC: C07D417/14
  • IPC: C07D417/14
2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors
Abstract:
The present invention relates to compounds of below Formula (I), physiologically functional derivatives or salts thereof, where the groups R1, R2, R3, R4, RA, X1, and A, as well as the variables n, m and p are detailed further herein. In another aspect, the present invention provides methods for their preparation, their medical use and pharmaceutical compositions comprising said compounds, physiologically functional derivatives, solvates or salts thereof.
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