A wire protection member includes: a flexible cylindrical wire protection tube; a cylindrical covering member that is formed on an outer circumferential surface of the wire protection tube by molding; and a locking tool that is formed integrally with the cylindrical covering member to allow the locking tool to be locked to a mounting hole of a vehicle body panel. The cylindrical covering member includes: a thick portion that is formed to be thicker in radial thickness than another outer circumferential portion in a circumferential direction on which at least the locking tool is provided to protrude; and a flat surface or a gentle curved surface that is formed in an outer surface of the thick portion and that is substantially parallel to a plane passing through an axis of the wire protection tube.