The present disclosure provides a method and an apparatus in a radio base station for inter-transceiver antenna calibration. The method comprises collecting a first phase difference between a first signal and a first reception signal and a second phase difference between a second signal and a second reception signal. The first signal is transmitted through a reference transmission path of a first transceiver and received through a reference reception path of a second transceiver as the first reception signal. The second signal is transmitted through a reference transmission path of the second transceiver and received through a reference reception path of the first transceiver as the second reception signal. The method further comprises determining and compensating for an inter-loop phase response difference between a first reference path loop of the first transceiver and a second reference path loop of the second transceiver by subtracting the second phase difference from the first phase difference. The first reference path loop consists of the reference transmission path and the reference reception path of the first transceiver, and the second reference path loop consists of the reference transmission path and the reference reception path of the second transceiver.