A robust liver function quantification algorithm to quantify regional and global liver function using temporally sparse-sampled multi-phase MRI with gadoxetic-acid injection is provided. The liver function quantification algorithm may be utilized in a liver function analysis server and indications of a patient's liver function may be provided for display on a healthcare professional's network-enabled device. The use of a single clinical multi-phase MRI with gadoxetic-acid injection may provide 1) regional liver function assessment, 2) global liver function assessment, and 3) risk analysis for future liver intervention.