Invention Grant
- Patent Title: MTAB-TA-Coated gold nanorods and method of fabrication
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Application No.: US15379581Application Date: 2016-12-15
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Publication No.: US10010508B1Publication Date: 2018-07-03
- Inventor: Anthony B Polito , Saber M Hussain
- Applicant: The United States of America, as represented by the Secretary of the Air Force
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Air Force
- Current Assignee: The United States of America as represented by the Secretary of the Air Force
- Current Assignee Address: US DC Washington
- Agency: AFMCLO/JAZ
- Agent Timothy Barlow
- Main IPC: A61K9/28
- IPC: A61K9/28 ; A61K9/20 ; A61K33/24

Abstract:
11-mercaptoundecyl trimethylammonium bromide gold nanorod (MTAB-GNR) coated with tannic acid (TA), useful for biological cellular imaging. A method of synthesizing tannic acid-coated 11-mercaptoundecyl trimethylammonium bromide gold nanorods (MTAB-TA GNRs) comprising presenting 11-mercaptoundecyl trimethylammonium bromide gold nanorods (MTAB-GNRs) in solution; functionalizing the MTAB-GNRs with tannic acid (TA) added to the MTAB-GNRs, the tannic acid configured to form a coating around the MTAB-GNRs forming MTAB-TA GNRs. The functionalizing step may further comprise adding a sodium chloride solution to the MTAB-TA GNR solution, and/or adding a MOPS buffer to the solution of tannic acid with MTAB-GNRs, and the tannic acid MTAB-GNR solution may be vortexed after each step. The MTAB-TA GNR solution may be centrifuged to separate the MTAB-TA GNRs from residual tannic acid and supernatant, and sterile water may be added to the MTAB-TA GNR solution and centrifuging performed to remove residual tannic acid from the MTAB-TA GNRs.
Public/Granted literature
- US20180169023A1 MTAB-TA-Coated Gold Nanorods and Method of Fabrication Public/Granted day:2018-06-21
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