![Active metabolite of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate and dimesylate dihydrate salt of active metabolite](/docs/US/2018-07-03/US10010527B2/abs.jpg.600x600.jpg)
- Patent Title: Active metabolite of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate and dimesylate dihydrate salt of active metabolite
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Application No.: US15504014Application Date: 2014-10-20
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Publication No.: US10010527B2Publication Date: 2018-07-03
- Inventor: Ramakrishna Nirogi , Ramasastri Kambhampati , Anil Karbhari Shinde , Venkateswarlu Jasti
- Applicant: SUVEN LIFE SCIENCES LIMITED
- Applicant Address: IN Hyderabad, Andhra
- Assignee: SUVEN SCIENCES LIMITED
- Current Assignee: SUVEN SCIENCES LIMITED
- Current Assignee Address: IN Hyderabad, Andhra
- Agency: IPHorgan Ltd.
- Priority: IN4011/CHE/2014 20140816
- International Application: PCT/IN2014/000667 WO 20141020
- International Announcement: WO2016/027276 WO 20160225
- Main IPC: A61K31/4035
- IPC: A61K31/4035 ; C07D209/04 ; C07D403/06 ; C07C317/14 ; C07C309/02
![Active metabolite of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate and dimesylate dihydrate salt of active metabolite](/abs-image/US/2018/07/03/US10010527B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to active metabolite of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole dimesylate monohydrate of formula (I). The present invention is also directed to dimesylate dihydrate salt of formula (II). The compounds of formula (I) and formula (II) are useful in the treatment of various disorders that are related to 5-HT6 receptor antagonist.
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