Invention Grant
- Patent Title: Factor VIII chimeric and hybrid polypeptides, and methods of use thereof
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Application No.: US14131600Application Date: 2012-07-06
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Publication No.: US10010622B2Publication Date: 2018-07-03
- Inventor: Jennifer A. Dumont , Susan Low , Alan J. Bitoni , Glenn Pierce , Alvin Luk , Haiyan Jiang , Byron McKinney , Matt Ottmer , Jurg Sommer , Karen Nugent , Lian Li , Robert Peters
- Applicant: Jennifer A. Dumont , Susan Low , Alan J. Bitoni , Glenn Pierce , Alvin Luk , Haiyan Jiang , Byron McKinney , Matt Ottmer , Jurg Sommer , Karen Nugent , Lian Li , Robert Peters
- Applicant Address: US MA Waltham
- Assignee: Bioverativ Therapeutics Inc.
- Current Assignee: Bioverativ Therapeutics Inc.
- Current Assignee Address: US MA Waltham
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/US2012/045784 WO 20120706
- International Announcement: WO2013/009627 WO 20130117
- Main IPC: C07K14/755
- IPC: C07K14/755 ; A61K47/48 ; A61K38/37 ; G01N33/86 ; A61K47/60 ; A61K47/68
Abstract:
The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
Public/Granted literature
- US20140294821A1 FACTOR VIII CHIMERIC AND HYBRID POLYPEPTIDES, AND METHODS OF USE THEREOF Public/Granted day:2014-10-02
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