- Patent Title: Polycyclic pyridone derivative having integrase inhibitory activity
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Application No.: US15502884Application Date: 2015-08-21
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Publication No.: US10011613B2Publication Date: 2018-07-03
- Inventor: Tomokazu Yoshinaga , Kouhei Nodu
- Applicant: Shionogi & Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: SHIONOGI & CO., LTD.
- Current Assignee: SHIONOGI & CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2014-169776 20140822
- International Application: PCT/JP2015/073487 WO 20150821
- International Announcement: WO2016/027879 WO 20160225
- Main IPC: C07D513/14
- IPC: C07D513/14 ; C07D471/04 ; C07D471/14 ; C07D471/22 ; C07D498/14 ; C07D498/22

Abstract:
The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses, in particular, HIV and drug-resistant strains thereof. Thus, the compound is useful in preventing or treating various diseases, viral infections (for example, AIDS), and the like in which integrase participates.
Public/Granted literature
- US20170226128A1 POLYCYCLIC PYRIDONE DERIVATIVE HAVING INTEGRASE INHIBITORY ACTIVITY Public/Granted day:2017-08-10
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