Invention Grant
- Patent Title: Method for producing soluble FcR as Fc-fusion with inert immunoglobulin Fc-region and uses thereof
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Application No.: US14611645Application Date: 2015-02-02
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Publication No.: US10011644B2Publication Date: 2018-07-03
- Inventor: Petra Rueger , Tilman Schlothauer , Stefan Seeber
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Grant Kalinowski
- Priority: EP12179025 20120802
- Main IPC: C07K14/705
- IPC: C07K14/705 ; G01N33/68 ; C07K14/735
Abstract:
Herein is a fusion polypeptide with the formula R1-FC-R2, wherein R1 denotes a first Fc-receptor, R2 denotes a second Fc-receptor, and FC denotes a heavy chain Fc-region polypeptide, wherein R1 or R2 or both are present, wherein FC does not substantially bind to R1 and/or R2 and uses thereof.
Public/Granted literature
- US20150140683A1 METHOD FOR PRODUCING SOLUBLE FcR AS Fc-FUSION WITH INERT IMMUNOGLOBULIN Fc-REGION AND USES THEREOF Public/Granted day:2015-05-21
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