Invention Grant
- Patent Title: Methods and compositions for the specific inhibition of HIF-1α by double-stranded RNA
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Application No.: US14952909Application Date: 2015-11-25
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Publication No.: US10011834B2Publication Date: 2018-07-03
- Inventor: Bob D. Brown , Henryk T. Dudek
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: DICERNA PHARMACEUTICALS, INC.
- Current Assignee: DICERNA PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: MH2 Technology Law Group, LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/113 ; A61K31/713
Abstract:
This invention relates to compounds, compositions, and methods useful for reducing HIF-1α target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
Public/Granted literature
- US20160177303A1 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF HIF-1a BY DOUBLE-STRANDED RNA Public/Granted day:2016-06-23
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