Invention Grant
- Patent Title: Alphaviral vectors and cell lines for producing recombinant proteins
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Application No.: US14892829Application Date: 2014-05-20
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Publication No.: US10011847B2Publication Date: 2018-07-03
- Inventor: Alejandro Aranda , Jaione Bezunartea Bezunartea , Cristian Smerdou Picazo , Damaso Molero Sánchez , Edita Mistiene , Andreu Soldevila Fàbrega , Paula Serrano Pérez-Nievas
- Applicant: 3P BIOPHARMACEUTICALS, S.L.
- Applicant Address: ES Noain (Navarra)
- Assignee: 3P BIOPHARMACEUTICALS, S.L.
- Current Assignee: 3P BIOPHARMACEUTICALS, S.L.
- Current Assignee Address: ES Noain (Navarra)
- Agency: Moore & Van Allen, PLLC
- Agent Tristan A. Fuierer
- Priority: ES201330722 20130520
- International Application: PCT/ES2014/070416 WO 20140520
- International Announcement: WO2014/188042 WO 20141127
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C12N7/00
Abstract:
The present invention relates to polynucleotides and alphaviral vectors for the expression of genes of interest in mammalian cells. Additionally, the invention relates to cells which comprise said polynucleotides and alphaviral vectors and are capable of stably expressing one or more genes of interest. The invention also relates to methods for obtaining said cells, to methods for expressing a gene of interest in said cells, and to methods for replacing the gene of interest stably expressed by said cells with another gene of interest.
Public/Granted literature
- US20160208286A1 ALPHAVIRAL VECTORS AND CELL LINES FOR PRODUCING RECOMBINANT PROTEINS Public/Granted day:2016-07-21
Information query
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