Invention Grant
- Patent Title: Methods for detecting enhanced NMDA receptor function and uses thereof
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Application No.: US15589257Application Date: 2017-05-08
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Publication No.: US10011863B2Publication Date: 2018-07-03
- Inventor: Robert H. Lipsky , Mingkuan Lin , Yang Jiang
- Applicant: INOVA HEALTH SYSTEM
- Applicant Address: US VA Falls Church
- Assignee: INOVA HEALTH SYSTEM
- Current Assignee: INOVA HEALTH SYSTEM
- Current Assignee Address: US VA Falls Church
- Agency: Polsinelli PC
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12Q1/68 ; C12Q1/6837
Abstract:
A method of determining the risk of cognitive decline in an aging subject is provided. The method includes analyzing an MRNA transcript including a GRIN2B nucleic acid sequence for the presence of the A allele in a biological sample obtained from the subject. The method also includes identifying the subject as having a decreased risk of cognitive decline when the A allele is present.
Public/Granted literature
- US20170349943A1 METHODS FOR DETECTING ENHANCED NMDA RECEPTOR FUNCTION AND USES THEREOF Public/Granted day:2017-12-07
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