A refrigeration system and a method eliminate compressor-generated noise within a predetermined interval during operation of the refrigerator system wherein an interior of a refrigerator normally is maintained within a desired cool temperature range by operation of a compressor-driven refrigeration device. A thermo-electric refrigeration device is placed in communication with the interior of the refrigerator for cooling the interior of the refrigerator. A control system is coupled with the compressor-driven refrigeration device and with the thermo-electric refrigeration device, and is configured to discontinue operation of the compressor-driven refrigeration device for the duration of the predetermined interval, and to activate the thermo-electric refrigeration device during the predetermined interval so as to maintain the interior of the refrigerator within the desired cool temperature range, while compressor-generated noise associated with operation of the compressor-driven refrigeration device is discontinued.