Systems and methods are presented for operating a vehicle camera system to detect, identify, and mitigate camera lens contamination. An image is received from a camera mounted on the vehicle and one or more metrics is calculated based on the received image. The system determines whether a lens of the camera is contaminated based on the one or more calculated metrics and, if so, determines a type of contamination. A specific mitigation routine is selected form a plurality of mitigation routines based on the determined type of contamination and is applied to the received image to create an enhanced image. The enhanced image is analyzed to determine whether the contamination is acceptably mitigated after application of the selected mitigation routine and a fault condition signal is output when the contamination is not acceptably mitigated.