Systems and methods for processing a segmented volume from magnetic resonance images that corresponds to a nerve are provided. The segmented volume can be processed to generate a report that provides complementary information on the state or condition of tissues contained in the segmented nerve volume. For example, the segmented volume can be processed to identify regions of suspected inflammation, or other pathology such as demyelination, of the nerve tissue contained in the segmented volume. The systems and methods described here provide a user-defined approach to identifying regions of suspected inflammation, or other pathology, in a segmented nerve volume.