Disclosed is a system for mitigating co-channel interference (CCI) caused due to narrow multiband signal in white space (WS) modems. The system includes a base-station that includes a base-station transmitter and a base-station receiver. The base-station receiver receives an orthogonal frequency division multiplexing signal (OFDM) from one or more customer premises equipment (CPE) transmitters. An interference detection module detects a presence of co-channel interference in carriers of the OFDM signal and determines co-channel interference affected carriers. A dynamic notch filter module receives the central interference carriers from interference detection module and mitigates the co-channel interference of co-channel interference affected carriers without affecting frame detection capability of the system. The base-station transmitter includes an interference aware frequency interleaver that spreads co-channel interference affected carriers based on interference specific interleaving parameters and frequency de-interleaving is performed corresponding to frequency interleaving in the base-station receiver.