Invention Grant
- Patent Title: Hydrochloride salt of((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-D]pyrimidin-7-YL}-2-hydroxycyclopentyl) methyl sulfamate
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Application No.: US14879151Application Date: 2015-10-09
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Publication No.: US10016427B2Publication Date: 2018-07-10
- Inventor: Ian G. Armitage , Reenu Chopra , Martin Ian Cooper , Marianne Langston , Steven P. Langston , Stepan Vyskocil
- Applicant: Millennium Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmacetuicals, Inc.
- Current Assignee: Millennium Pharmacetuicals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61P35/02 ; A61P35/04 ; C07D487/04
![Hydrochloride salt of((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-D]pyrimidin-7-YL}-2-hydroxycyclopentyl) methyl sulfamate](/abs-image/US/2018/07/10/US10016427B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed is a compound of formula (I): crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula (I), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula (I), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.
Public/Granted literature
- US20170000792A9 HYDROCHLORIDE SALT OF((1S,2S,4R)-4--2-HYDROXYCYCLOPENTYL) METHYL SULFAMATE Public/Granted day:2017-01-05
Information query
IPC分类: