Invention Grant
- Patent Title: Small molecule drug conjugates
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Application No.: US15431310Application Date: 2017-02-13
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Publication No.: US10016511B2Publication Date: 2018-07-10
- Inventor: Nikolaus Krall , Willy Decurtins , Dario Neri , Jörg Scheuermann , Moreno Wichert
- Applicant: Philochem AG
- Applicant Address: CH Zurich
- Assignee: Eth Zurich
- Current Assignee: Eth Zurich
- Current Assignee Address: CH Zurich
- Agency: Sunstein Kann Murphy & Timbers LLP
- Priority: GB1401819.6 20140203; GB1407530.3 20140429; GB1419994.7 20141110
- Main IPC: A61K31/433
- IPC: A61K31/433 ; A61K47/48 ; A61K51/08 ; A61K38/05
Abstract:
A binding moiety (B) for Carbonic Anhydrase IX (CAIX), the binding moiety comprising: The binding moiety is univalent, bivalent, or multivalent. A targeted therapeutic agent may comprise the binding moiety. The invention also includes a method for treating a disease expressing elevated levels of CAIX by administering the targeted therapeutic agent.
Public/Granted literature
- US20170224831A1 Small Molecule Drug Conjugates Public/Granted day:2017-08-10
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