A method is disclosed for operating an internal combustion engine having a turbocharger and an exhaust gas recirculation pipe fluidly connecting an exhaust system to an air intake system upstream of a compressor of the turbocharger. A first value of a parameter indicative of the density of a mixture of fresh air and exhaust gas in the air intake system is determined. A flowing of exhaust gas through the exhaust gas recirculation pipe is interrupted if the first value is lower than a first reference value thereof.