Invention Grant
- Patent Title: Methods for treating inflammatory and other diseases and the use of biomarkers as predictors of clinical sensitivity to treatment with apremilast
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Application No.: US15286302Application Date: 2016-10-05
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Publication No.: US10018637B2Publication Date: 2018-07-10
- Inventor: Peter H. Schafer , Matthew William Burnell Trotter
- Applicant: CELGENE INTERNATIONAL II SARL
- Applicant Address: CH
- Assignee: CELGENE INTERNATIONAL II SARL
- Current Assignee: CELGENE INTERNATIONAL II SARL
- Current Assignee Address: CH
- Agency: Jones Day
- Main IPC: G01N33/68
- IPC: G01N33/68 ; A61K31/4035
Abstract:
Provided herein are methods for predicting the clinical sensitivity of an inflammatory disease (e.g., ankylosing spondylitis) and a subject's response to treatment with apremilast using the level of a biomarker (e.g., MCP1). Also provided herein are methods for treating an inflammatory disease.
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