An information handling system is provided. The information handling system includes an information handling device having one or more processors in communication with a network interface card. The network interface card includes one or more interfaces for receiving frames the information handling device is coupled to an external network device. The device also includes a memory that is in communication with the one or more processors and stores a classification matrix. The classification matrix is used to generate a current interrupt throttling rate from a plurality of candidate interrupt throttling rates that are applied to the received frames according to at least two properties of each frame of the received frames. A method for providing adaptive interrupt coalescing is also provided.