Invention Grant
- Patent Title: Ropinirole-containing adhesive patch
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Application No.: US14647725Application Date: 2013-11-28
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Publication No.: US10022336B2Publication Date: 2018-07-17
- Inventor: Katsuyuki Inoo , Akiko Katayama , Daiki Takano
- Applicant: Teikoku Seiyaku Co., Ltd.
- Applicant Address: JP Higashikagawa-shi
- Assignee: Teikoku Seiyaku Co., Ltd.
- Current Assignee: Teikoku Seiyaku Co., Ltd.
- Current Assignee Address: JP Higashikagawa-shi
- Agency: Crowell & Moring LLP
- Priority: JP2012-262143 20121130
- International Application: PCT/JP2013/082055 WO 20131128
- International Announcement: WO2014/084311 WO 20140605
- Main IPC: A61K9/70
- IPC: A61K9/70 ; A61K31/4045 ; A61K47/06

Abstract:
A patch containing free ropinirole (ropinirole in free form) in an adhesive base is provided, in which the patch exhibits favorable and continuous transdermal absorbability, high drug stability, and excellent adhesiveness. A transdermal absorption patch includes free ropinirole added to an adhesive base that contains a styrene-isoprene-styrene block copolymer (SIS), one or two or more tackifier resins containing a rosin-based resin, and a softener. The transdermal absorption patch is characterized in that the compounding ratio of the rosin-based resin to the free ropinirole represented as the ratio of the weight of the combined rosin-based resin to the free ropinirole is 3.5 to 8.0. In particular, a ropinirole-containing patch wherein the rosin-based resin is a hydrogenated rosin glycerol ester and the softener is liquid paraffin is provided.
Public/Granted literature
- US20150297532A1 Ropinirole-Containing Adhesive Patch Public/Granted day:2015-10-22
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