Invention Grant
- Patent Title: Compounds for treatment of cancer
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Application No.: US14773265Application Date: 2014-03-05
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Publication No.: US10022356B2Publication Date: 2018-07-17
- Inventor: Jin Wang , Jianjun Chen , Duane D. Miller , Wei Li
- Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Applicant Address: US TN Knoxville
- Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Current Assignee Address: US TN Knoxville
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- International Application: PCT/US2014/020858 WO 20140305
- International Announcement: WO2014/138279 WO 20140912
- Main IPC: A61K31/42
- IPC: A61K31/42 ; A61K31/44 ; A61K31/335 ; A61K31/4178 ; A61K31/337 ; A61K31/437 ; A61K31/506 ; A61K31/519 ; A61K31/4174 ; A61K31/4164 ; A61K31/435

Abstract:
The present invention relates to pharmaceutical compositions for treating cancer comprising BRAF inhibitors, (e.g. vemurafenib) and/or MEK inhibitor, (e.g. trametinib, RO5068760), in combination with anti-tubulin compounds of the invention or other known tubulin inhibitors, and using such compositions for treating cancer such as melanoma, drug-resistant cancer, and cancer metastasis.
Public/Granted literature
- US20160015688A1 COMPOUNDS FOR TREATMENT OF CANCER Public/Granted day:2016-01-21
Information query